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Can you say for example "Wer sind sie?" or do you use something else for that question?
"Wer" is correct in plural. so "Wer sind sie?" is also a correct sentence.
The word "wer" is correct, but if you are trying to ask "who are those people?", you should better use something like "wer sind diese Leute?", instead of "wer sind sie?".
The latter sounds way more natural ;)
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